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Nmn supplements

December 7, 2019 by protechcarpetprotection  


A new study published in Nature Metabolism finally reveals the answer to how NMN enters the cell in order to become NAD+ and that it does not need to convert into NR to do so.

PURE NMN®  Change Your Life


Scientists have known about the vital role of NAD since 1906. Since then, they’ve learned NAD is found in every living cell, and that it powers the mitochondria, which keeps almost every tissue in the body healthy. In 2007, a landmark study by Dr. David Sinclair uncovered a unique form of vitamin B3 that could safely and efficiently raise NAD levels. We’re bringing PURE NMN ® to everyone.



Alzheimer’s Disease and Neurological Function

Alzheimer’s disease is on the rise, with nearly 5.7 million Americans living with the disease; this number is projected to rise to 14 million by 2050. Dietary and lifestyle changes are crucial for preventing and slowing the progression of Alzheimer’s disease. NMN can help bolster the beneficial effects of dietary and lifestyle changes in Alzheimer’s disease prevention by preserving the health of the brain. NMN inhibits the buildup of amyloid-beta, an abnormal protein implicated in the adverse brain changes characteristic of Alzheimer’s disease, while also decreasing synaptic loss and brain inflammation. (3) These effects slow down the process of brain degeneration and may even help reverse the progression of Alzheimer’s disease.
The neurological benefits of NMN are not limited to Alzheimer’s disease; NMN also maintains the brain’s population of neural stem cells and attenuates brain injury after head trauma. (4, 5) These findings suggest that NMN may have significant therapeutic benefits for athletes who have suffered concussions, and other individuals recovering from head injuries.


Heart Disease

The human heart requires a continuous supply of ATP to fuel its muscular contractions and sustain life. Interruptions in the heart’s ATP supply can impair cardiac and vascular function and contribute to the development of cardiovascular disease. By enhancing the biosynthesis of NAD+, an essential substrate in ATP-producing reactions, NMN boosts cardiac ATP levels and significantly improves heart health. In fact, supplementation with NMN may even prevent myocardial infarctions (heart attacks) and heart failure! (6)  Importantly, NMN also reduces arterial aging and vascular dysfunction, two phenomena that play crucial roles in the pathogenesis of cardiovascular disease. (7)


Diabetes and Metabolic Syndrome

In pancreatic beta cells, NAD+ regulates insulin secretion in response to the ingestion of dietary glucose. (8, 9)  NAD+ also governs insulin activity and glucose homeostasis in skeletal muscle, the liver, and adipose tissue. Research indicates that the normal biosynthesis of NAD+ is severely compromised in diabetic individuals, leading to insulin resistance and glucose intolerance.
By restoring NAD+ levels in skeletal muscle, the liver, and adipose tissue, NMN improves insulin sensitivity and may help reverse the course of diabetes. NMN also corrects dyslipidemia, a condition in which cholesterol and triglycerides are elevated in the bloodstream. (10, 11)
Dyslipidemia and insulin resistance are key features of metabolic syndrome, a disorder that afflicts a whopping 35 percent of U.S. adults and significantly increases the risk of diabetes, heart disease, and stroke. Finally, NMN normalizes the expression of genes that govern circadian rhythms and decreases oxidative stress and inflammation; altered circadian rhythms, oxidative stress, and chronic inflammation are three of the most important underlying causes of type 2 diabetes and metabolic syndrome. (12)
These fascinating findings indicate that NMN can play an essential adjunct role, alongside dietary and lifestyle changes, in the prevention and treatment of type 2 diabetes and metabolic syndrome.


DNA Repair

Your DNA serves as the blueprint for your body’s physiological function. When DNA expression goes awry due to factors such as an unhealthy diet, environmental toxins, and aging, your body’s blueprint is intrinsically altered; this disrupts normal body function and contributes to the development of chronic health conditions such as cancer, diabetes, and neurological dysfunction. NMN helps prevent adverse changes in gene expression by repairing damaged DNA. (13)



Weight gain and weight loss resistance are common struggles for countless Americans. NMN is a powerful nutraceutical ally in weight loss efforts because it reverses insulin resistance, improves glucose tolerance, and ameliorates mitochondrial dysfunction, three factors that contribute to stubborn weight issues. (14, 15)


Human Trials

While most of the available research on NMN involves animal studies, human clinical trials have been undertaken, and the results are expected to be released within the next year. In the meantime, the plethora of beneficial effects demonstrated by NMN in animal studies, and the complete lack of adverse effects, suggests that NMN supplementation may be a valuable tool to add to your healthy lifestyle today!

The Boston Supplement Inc
Our mission is to turn critical scientific advancements into accessible consumer products.
Working directly with the world’s leading scientists and clinicians, we translate research into solutions you can access today.
Why now ? Because we believe that advancements in scientific research are leading to compelling new developments.
Landmark scientific discoveries in the past 20 years — from mapping the human genome to creating a more complete understanding of cellular metabolism — offer a path to proactive health solutions.
We founded PURE NMN because we believe everyone should benefit directly from this compelling research. Working in partnership with the world’s leading scientists and research universities, PURE NMN is creating a new category in the industry by translating advances in science into effective products we can easily incorporate into everyday life.
We believe this is a fundamentally new approach to wellness.
Science, Our Core Value
A fully-loaded product pipeline in various stages of clinical development, Nobel Prize-winning advisors, partnerships with Harvard, Oxford, and MIT — and much more. At the heart of each one of our initiatives is a commitment to rigorous scientific research.

Dr. Nicole W