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Lorcaserin Hydrochloride Fat Burning Drug Lorcaserin HCl 856681-05-5

August 21, 2019 by freemexy  

Lorcaserin Hydrochloride Fat Burning Drug Lorcaserin HCl 856681-05-5

 

Lorcaserin Hydrochloride (Belviq) is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight† adults with a weight-related medical problem, or obese adults, lose weight and keep it off. It is not known if BELVIQ when taken with other prescription, over-the-counter, or herbal weight-loss products is safe and effective. It is not known if BELVIQ changes your risk of heart problems, stroke, or death due to heart problems or stroke.Lorcaserin powder

Check It Before You Use
Lorcaserin HCl is an FDA-approved prescription weight-loss medication that, when used with diet and exercise, can help some overweight adults with a weight-related medical problem, or obese adults, lose weight and keep it off.
lorcaserin hydrochlorideis a serotonin 2C receptor agonist. It hasbeen shown to decrease food consumption and promote SA tiety by selectivelyactivating serotonin 2C receptors in the brain.
Lorcaserin HCl is specifically indicated as an adjunct to a reduced-calorie diet andincreased physical activity for chronic weight management in clinically obeseadults (BMI of 30 kg/m2 or greater) and overweight adults (BMI of 27 kg/m2 orgreater) with at least one weight-related comorbid condition.
Lorcaserin HCl is supplied as a tablet designed for oral administration. The recommendeddose is one 10mg tablet twice daily. Use of Lorcaserin HCl should be discontinued if 5%weight loss is not achieved by week 12 of treatment.

Nootrpics Racetam Piracetam Powder for Brain Pill Liquid

August 21, 2019 by freemexy  

Nootrpics Racetam Piracetam Powder for Brain Pill Liquid

 

Piracetam is a nootropic supplement that has the ability to enhance memory and has stood the test of time making it a popular choice for those that want to enhance their cognitive abilities. It is known to allow your creative and logical thoughts to run together into a stream of higher level thinking and can increase the amount of knowledge that your brain can retain for later access.Oxiracetam powder

Benefits and Effects

Piracetam is most known for its ability to enhance cognitive function.

Piracetam won't make you more intelligent per se, but especially when combined with a choline supplement, it has the ability to improve your memory quite substantially. What piracetam does, in layman's terms, is increase the communication between the left and right part of your brain by increasing the blood flow between these two parts. Essentially, your logical thinking part of your mind will share more with the more imaginative part of your brain. This is why it increases memory in the brain. You can feel the fluidity of your thoughts increase, ideas seem to flow, if nootropics don't increase memory, I can certainly say they put your thoughts on a higher level.

Piracetam's effects are considered less strong compared to its more recent descendants but still remains a very popular choice for a well-rounded nootropic supplement. Many individuals use piracetam as a supplement to boost mental performance.

Piracetam has a large range of effective doses. A low baseline dose of 400 mg is the bottom of most suggested servings, while 800 mg is the median which many people take in a single sitting. This amount can be repeated three times a day with zero toxicity effects.

Although not applicable to every individual, the standard dosage of piracetam is 1600 mg thrice a day in the starting. This dose may vary if the patient is a child. The recommended piracetam dosage varies based on the reason of use, usually ranging from 1.6-9.6 grams daily (2-12 pills daily). Some people report better results when taking 1-2 pills per hour for 4-6 hours or taking 4-8 pills at once for the first few days to notice an effect.

Carphedon;phenylpiracetam, 4-Phenyl-2-pyrrolidone-1-acetamide

August 21, 2019 by freemexy  

Carphedon;phenylpiracetam, 4-Phenyl-2-pyrrolidone-1-acetamide

 

Carphedon powder Product Basic Information
Product Name:4-phenyl-2-pyrrolidone-1-acetamide
Synonyms:2-(2-Oxo-4-phenylpyrrolidin-1-yl)acetamide
CAS Number:77472-70-9
MF:C12H14N2O2
MW:218.25
EINECS:/
Chemical Properties
Appearance: white soild
Assay: 98%
Melting Point:/ ℃(lit.)
Boiling Point:486.4℃at 760mmHg
Stability:normal temperature and pressure
Usage:Nootropics
Safety Information
RIDADR :Non DG
Package: 50g,1kg, 25kg, bulk

PREDATOR NUTRITION 9-MBC REVIEW

August 21, 2019 by freemexy  

PREDATOR NUTRITION 9-MBC REVIEW

 

9-MBC is a nootropic agent of surprising potency and multifaceted utility, as it possesses many mechanisms of action:
- It potently stimulates neuron and neurite growth
- It is neuroprotective, and can protect the brain and CNS from toxin-induced damage
- It is strongly dopaminergic and possesses stimulant properties, thus can improve cognitive markers like reaction time
- It improves the efficiency of the respiratory chain, leading to potentially enhanced cognitive and athletic performance
- It increases the rate of neurotrophin synthesis, which can lead to memory and learning enhancement. It is, in short, the most well-rounded and effective nootropic available. It delivers clean stimulation, and sharper, faster thinking. And unlike so many other nootropics, the effects of which are disappointingly transient, the pro-cognitive benefits derived from 9-MBC should be very long-lasting.
WHEN
9-MBC's effects become apparent within a few days of use. It can be taken on a regular or irregular schedule, as preferred.
WHO
9-MBC is suitable for adult men and women of all ages. It is not recommended for persons under the age of 21. Furthermore, exceeding the recommended dosage is, furthermore, not recommended.9-methyl-9H-pyrido[3,4-b]indole

Hydrapharm has done it again. 9-MBC is an industry-leading, best-in-class nootropic which delivers lasting and prolonged effects. Unlike so many other nootropics, which wear-off after mere hours, 9-MBC promotes real neuron and neurite growth in a highly significant manner for long-term memory and cognitive enhancement.

And that's just the beginning. 9-MBC is also a stimulant, which delivers clean energy, sharp focus, and enhanced reaction times. This is due primarily to the fact that it boosts dopamine and neurotrophin synthesis, leading to a dopaminergic stimulant effect.

9-MBC is ideal for two types of people: First, those who engage in cognitively difficult or demanding tasks, particularly those which require sustained focus and mental energy. Second, athletes looking to boost their reflexes and reaction times.

9-MBC can be taken on a daily basis, preferably on a 4-weeks-on/4-weeks-off cycle or on an irregular "as-needed" basis. Generally, people who fall into the first aforementioned category, i.e., those looking for long-term cognitive enhancement are advised to use the product on a daily basis, whereas those looking for short-term boosts in energy and reaction time would likely find more irregular use preferable. 

Brain Benefits of L-Theanine

August 21, 2019 by freemexy  

Brain Benefits of L-Theanine

 

There's been a resurgence of interest in the anxiety-relieving powers of L-theanine, an amino acid found in green tea.1

Discoveries over the past two years have uncovered exciting additional properties of this nutrient best known for inducing calming, tranquilizing effects while simultaneously improving alertness.L-theanine

In this Research Update, we examine how L-theanine acts in the brain, and review compelling new studies on its actions that include potentially reduced risk of stroke and less brain damage if an ischemic stroke were to occur.
L-theanine relieves anxiety in large part because it bears a close resemblance to the brain-signaling chemical glutamate. L-theanine produces the opposite effect in the brain.

While glutamate is the brain's most important excitatory neurotransmitter, L-theanine binds to the same brain cell receptors and blocks them to glutamate's effects. This action produces inhibitory effects.1,2 That inhibition to brain overactivity has a calming, relaxing effect in which anxiety fades.3

In addition to blocking excitatory stimuli at glutamate receptors in the brain, L-theanine also stimulates production of the inhibitory, relaxing neurotransmitter GABA, adding to its calming, anti-anxiety effects.2

Unlike prescription anti-anxiety drugs, however, some of which mimic GABA's effects, L-theanine produces its anti-anxiety effects without producing sleepiness or impairing motor behavior.4 In fact, L-theanine has been shown in human studies to moderately improve alertness and attention while exerting its anxiety-reducing effects.5

Of particular interest are studies showing that L-theanine supplementation prevents the abrupt rise in blood pressure that some people experience under stress.1 The reason this is so critical is that many people have normal blood pressure readings at rest that spike up to dangerously high levels when subjected to stressful situations.

These periods of surging blood pressure inflict massive arterial damage and are the main reason why at-home and at-office blood pressure testing are so important.
Scientists are now increasingly interested in applications for L-theanine far beyond its anti-anxiety properties. Excessive glutamate stimulation of brain cells (excitotoxicity) is a factor in development of long-term neurodegenerative disorders, stroke, and schizophrenia.6,7 Therefore, L-theanine's glutamate-blocking capabilities make it promising for neuroprotection and prevention in these areas.

And while its deeper mechanisms are still under investigation, there is tantalizing evidence that L-theanine influences expression of genes in brain areas responsible for fear and aggression (amygdala) and memory (hippocampus), helping to balance the behavioral responses to stress, and potentially improve conditions such as mood disorders, post-traumatic stress disorder (PTSD), and substance dependence.8

PRL-8-53 REVIEW /WHAT IS PRL-8-53 ?

August 21, 2019 by freemexy  

PRL-8-53 REVIEW /WHAT IS PRL-8-53 ?

 

PRL-8-53, the newest nootropic, also known by its chemical name Methyl 3-[2-[benzyl(methyl)amino]ethyl]benzoate is a synthetic nootropic supplement. It was developed in the 1970′s by Dr. Nikolaus Hansl at Creighton University in Nebraska. It has had some human studies which showed positive responses in cognitive function. One study showed that the compound could help retrieve lost memories (hypermnesia).PRL-8-53 powder

HOW DOES PRL-8-53 WORK?
PRL-8-53 is derived from the combination of benzoic acid and phenylmethylamine. The chemical structure formed from the combination of these two compounds results in a compound that can interact with cholinergic receptors, which are involved in modulating memory and learning processes within the brain. PRL-8-53 is also known to potentiate (increase the effect of) dopamine and partially inhibit serotonin receptors. Dr. Nikolaus Hansl believed that this effect profile would likely lead to a shift of the balance in CNS neurotransmitter systems and lead to improved intellectual functioning.

There has only been one human clinical study preformed to evaluate the effects of the drug and it showed an improvement in verbal memory, visual reaction time and motor control, especially in those over the age of 30. Older people tend to be more subject to memory and cognitive decline, therefore, memory and cognitive enhancing supplements tend to work better on them.

PRL-8-53 BENEFITS/FUNCTIONS :
Enhance mental intelligence
Boost memory and leaning capabilities
Improve brain power to solve problems and protect it from any chemical or physical injury
Enhance motivation level
Enhance the control of cortical/subcortical brain mechanism
Improve sensory perception

Weight loss drug lorcaserin found safe in large study

August 21, 2019 by freemexy  

Weight loss drug lorcaserin found safe in large study

 

Eisai's weight loss drug lorcaserin does not increase people's risk of major cardiovascular events, according to data from a study of 12,000 overweight or obese patients.

Everyone in the study, which was funded by Eisai, had atherosclerotic cardiovascular disease or multiple risk factors for heart disease.

With half the study participants tracked for at least three years, there was no difference in the combined risk of heart attack, stroke or any type of cardiovascular death between people taking lorcaserin and people taking a dummy pill.Lorcaserin powder

That outcome was seen in 2.0 percent of lorcaserin-treated subjects per year versus 2.1 percent of the placebo group.

When researchers also considered cases of heart failure, hospitalization for chest pain and the need to reopen clogged arteries in the heart, rates were 4.1 percent per year with lorcaserin and 4.2 percent with placebo.

At the one-year mark, 38.7 percent of volunteers getting the drug and 17.4 percent getting placebo had lost at least 5 percent of their body weight.

A loss of 10 percent or more of body weight occurred in 14.6 percent of lorcaserin recipients and 4.8 percent of placebo patients.

The study, known as CAMELLIA-TIMI 61, was reported at the European Society of Cardiology's Annual Congress in Munich and online in The New England Journal of Medicine.

"For now, the drug may best be used on a cautious basis according to the needs of individual patients," according to an editorial by Journal editor Dr. Julie Ingelfinger and Dr. Clifford Rosen of Tufts University School of Medicine in Boston.

"As in other reports on its use, the side effects of headache, fatigue, dizziness, diarrhea and nausea let to twice the number of discontinuations in the lorcaserin group as in the placebo group, although the total rates of discontinuation were similar in the two groups," they noted.

The drug, sold under the brand name Belviq, costs about $280 per month according to the website goodrx.com.

About 40 percent of Americans are obese.

In the past, several promising weight loss medications have been pulled from the market because of cardiovascular side effects.

Study patients were treated at 473 sites in eight countries. The drug, approved by the U.S. Food and Drug Administration in 2012, was given as a 10-mg dose twice daily.

Big discounting 3 Nootropic Powder Sunifiram Dm-235

August 21, 2019 by freemexy  

Big discounting 3 Nootropic Powder Sunifiram Dm-235

 

Our pros are lessen prices,dynamic sales team,specialised QC,sturdy factories,top quality services and products for Ibutamoren Mesylate , Hgh Human Growth , Fluoxymesterone Powder , All products are manufactured with advanced equipment and strict QC procedures in order to ensure high quality. Welcome customers new and old to contact us for business cooperation.DM-235 powder
Bremelanotide, also known as PT-141, is a melanocortin peptide hormone. Bremelanotide (PT-141) was developed from Melanotan II (MT-2) and can be regarded as a derivate from MT-2.
Bremelanotide (PT-141) is regarded as the only synthetic aphrodisiac. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Unlike and other related medications (PDE5s), PT-141 does not act upon the vascular system, but directly through the nervous system (hypothalamus) to increase desire. Cials and are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 are known to have a synergistic effect.
3.Product Applications:
Bremelanotide is a melanocortin peptide hormone. PT-141 binds to the melanocortin 4 receptor (MC4R) in particular in the brain. Nine out of ten volunteers experienced sexual arousal in trials. The aphrodisiac effects of Bremelanotide are in a class of its own.
Bremelanotide comes in 10mg and 2mg vial sizes. Peptides photographed at right are synthesized by the same laboratory, contain no filler and therefore the difference is visible. Freeze dried Melanotan peptides (PT-141) are very durable and stable. Most PT-141 comes in the industry standard 10mg size. The 2mg PT-141 is used more as a travel peptide or couples dose. As a lifestyle peptide, the 10mg product is a lot to consume and may offer up to 20 doses when dosing light. The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge for months. Nasal sprays, pre-mixed PT-141, pills and loose powder are not legitimate. There are successful reports of snorting and nasal spray experiences...however they are few and far between.
Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. The human PT-141 date is one where the dosage precedes the activity by at least a couple hours. When the stars align, hours after the injection, ...this is your window of opportunity, enjoy.

Supply CAS:314728-85-3 Nootropic powder Sunifiram

August 21, 2019 by freemexy  

Supply CAS:314728-85-3 Nootropic powder Sunifiram

 

What is Nootropic?
Nootropics also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that purportedly improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. Lyphar biotech produce kinds of Nootropics
,nootropics are thought to work by altering the availability of the brain's supply of neurochemicals (neurotransmitters, enzymes, andhormones), by improving the brain's oxygen supply, or by stimulating nerve growth.Noopept powder

What is Sunifiram ?

Nootropics are a category of drugs that are often referred to as "Smart Drugs." This title is earned because these drugs have provided benefits in the areas of attention span, cognitions, recall and overall memory enhancements that can improve one's mental performance. Sunifiram is one such drug. Unlike many of the drugs that fall under the heading of nootropics are all from the Racetam family except in the case of Sunifiram. Sunifiram is referred to as an ampakine because it gains its effectiveness through the increasing glycine receptor binding.
Function: 
1) Sunifiram is good at improved decision making
2)A greater ability to convert short-term memory into long-term memory
3)Improved motor skills via increased control over muscle contraction
4) Sunifiram can enhanced memory and retention of learned information and activities

Anti-NMDAR2A (GluN2A) (extracellular)-ATTO-488 Antibody

August 21, 2019 by freemexy  

Anti-NMDAR2A (GluN2A) (extracellular)-ATTO-488 Antibody


Immunohistochemical staining of immersion-fixed, free floating rat brain frozen sections using Anti-NMDAR2A (GluN2A) (extracellular)-ATTO-488 Antibody (#AGC-002-AG), (1:200) and Anti-SynGAP Antibody (#APZ-032), (1:200), followed by donkey-anti-rabbit-Cy3. A. GluN2A staining (green) appears in neuronal profiles (arrows). B. SynGAP staining (red) is detected mostly in apical dendrites (horizontal arrows) and in neuronal soma (vertical arrows). C. Merge of the two images demonstrates colocalization in some neurons (vertical arrows). Cell nuclei are stained with DAPI (blue).N-Methyl-D-Aspartic Acid

Anti-NMDAR2A (GluN2A) (extracellular) Antibody (#AGC-002) is a highly specific antibody directed against an extracellular epitope of the rat protein. The antibody can be used in western blot, immunoprecipitation, immunocytochemistry, and immunohistochemistry. It has been designed to recognize GluN2A from rat, mouse, and human samples.

Anti-NMDAR2A (GluN2A) (extracellular)-ATTO-488 Antibody (#AGC-002-AG) is directly labeled with an ATTO-488 fluorescent dye. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-488 label is analogous to the well known dye fluorescein isothiocyanate (FITC) and can be used with filters typically used to detect FITC. Anti-NMDAR2A (GluN2A) (extracellular)-ATTO-488 Antibody has been tested in immunohistochemistry and is especially suited for experiments requiring simultaneous labeling of different markers.